IgG4-related Skin Disease: Experience with Two Cases / 대한피부과학회지
Korean Journal of Dermatology
; : 197-201, 2018.
Article
em Ko
| WPRIM
| ID: wpr-713428
Biblioteca responsável:
WPRO
ABSTRACT
IgG4-related disease (IgG4-RD) is a new disease entity characterized by elevated serum IgG4 and infiltration of IgG4+ plasma cells in tissue. IgG4-RD can involve various organs, and skin could also be affected. The manifestations of IgG4-related skin disease (IgG4-RSD) are not characteristic, however it usually presents with multiple erythematous nodules or plaques with itching sensation. We report two cases of IgG4-RSD. Histological studies of these cases revealed infiltration of numerous plasma cells and mononuclear cells in the entire dermis. Some plasma cells were strongly positive for IgG4 stain. IgG4-RSD is a treatable disease with systemic corticosteroids. Thus, clinicians should obtain a biopsy and identify IgG4-positive cells for an accurate diagnosis.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Plasmócitos
/
Prurido
/
Sensação
/
Pele
/
Dermatopatias
/
Biópsia
/
Imunoglobulina G
/
Corticosteroides
/
Derme
/
Diagnóstico
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Ano de publicação:
2018
Tipo de documento:
Article