Trends of uterine carcinosarcoma in the United States / 부인종양
Journal of Gynecologic Oncology
;
: e22-2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-713663
ABSTRACT
OBJECTIVE:
Uterine carcinosarcoma (UCS) is a rare type of high-grade endometrial cancer (EC) that has been understudied with population-based statistics due to its rarity. This study examined temporal trends in the proportion of UCS among women with EC.METHODS:
This is a retrospective observational study examining The Surveillance, Epidemiology, and End Results program between 1973–2013. Primary EC cases were eligible for analysis, and a time-specific proportion of UCS was examined during the study period.RESULTS:
UCS was seen in 11,000 (4.7%) women among 235,849 primary EC cases. Mean age at UCS diagnosis increased from 65.9 to 71.7 years between 1973–1989 and then decreased from 71.7 to 67.0 years between 1989–2013 (both, p < 0.001). Proportion of Black women significantly increased during the study period (11.9%–20.0%, p < 0.001), whereas the proportion of White women decreased from 86.0% to 60.5% between 1987–2013 (p < 0.001). There was a significant increase in the proportion of UCS among primary EC from 1.7% to 5.6% between 1973–2013 (p < 0.001). Among type II ECs (n=76,118), the proportion of UCS also increased significantly from 6.0% to 17.5% between 1973–2013 (p < 0.001). An increasing proportion of UCS was seen in both young and older women but the magnitude of interval increase was larger in the older age group between 1973–2013 ( < 60 years, from 1.3% to 3.3%. p < 0.001; and ≥60 years, from 2.6% to 7.0%, p < 0.001).CONCLUSION:
Our study demonstrated that the proportion of UCS has significantly increased among EC, accounting for more than 5% in recent years.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estados Unidos
/
Carcinossarcoma
/
Estudos Retrospectivos
/
Neoplasias do Endométrio
/
Programa de SEER
/
Diagnóstico
/
Estudo Observacional
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Feminino
/
Humanos
País/Região como assunto:
América do Norte
Idioma:
Inglês
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2018
Tipo de documento:
Artigo
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