Patient with Systemic Lupus Erythematosus Combined with Erosive Arthritis was Treated Successfully with Tocilizumab: A Case Report
Journal of Rheumatic Diseases
; : 144-147, 2018.
Article
em En
| WPRIM
| ID: wpr-713813
Biblioteca responsável:
WPRO
ABSTRACT
Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease that frequently involves the joints at some stage during the disease course. Although lupus arthritis is usually non-erosive, approximately 5% of patients develop erosions. This paper reports a patient with SLE combined with erosive arthritis, who was treated successfully with tocilizumab. A 20-year-old female, who was first diagnosed with SLE at the age of 13 years, had been admitted frequently to hospital with disease flare-ups during the previous 3 years. Despite aggressive treatment, her arthritis became aggravated, particularly in both wrists and the right knee. Radiologically, erosive arthritis was noted in the wrists.The serum interleukin (IL)-6 level was elevated significantly along with the other inflammatory markers. After the tocilizumab treatment, the arthritis subsided with a normalization of the IL-6 level, suggesting that tocilizumab may be a suitable treatment for lupus erosive arthritis if the IL-6 level is high.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Artrite
/
Punho
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Interleucinas
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Interleucina-6
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Articulações
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Joelho
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Lúpus Eritematoso Sistêmico
Limite:
Female
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Humans
Idioma:
En
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2018
Tipo de documento:
Article