Review: optically-triggered phase-transition droplets for photoacoustic imaging
Biomedical Engineering Letters
;
(4): 223-229, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-714460
ABSTRACT
Optically-triggered phase-transition droplets have been introduced as a promising contrast agent for photoacoustic and ultrasound imaging that not only provide significantly enhanced contrast but also have potential as photoacoustic theranostic molecular probes incorporated with targeting molecules and therapeutics. For further understanding the dynamics of optical droplet vaporization process, an innovative, methodical analysis by concurrent acoustical and ultrafast optical recordings, comparing with a theoretical model has been employed. In addition, the repeatability of the droplet vaporization-recondensation process, which enables continuous photoacoustic imaging has been studied through the same approach. Further understanding the underlying physics of the optical droplet vaporization and associated dynamics may guide the optimal design of the droplets. Some innovative approaches in preclinical studies have been recently demonstrated, including sono-photoacoustic imaging, dual-modality of photoacoustic and ultrasound imaging, and super-resolution photoacoustic imaging. In this review, current development of optically triggered phase-transition droplets and understanding on the vaporization dynamics, their applications are introduced and future directions are discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Volatilização
/
Sondas Moleculares
/
Ultrassonografia
/
Nanomedicina Teranóstica
/
Métodos
/
Modelos Teóricos
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Biomedical Engineering Letters
Ano de publicação:
2018
Tipo de documento:
Artigo
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