Effect of Helicobacter pylori eradication on the regression of gastric polyps in National Cancer Screening Program
The Korean Journal of Internal Medicine
; : 506-511, 2018.
Article
em En
| WPRIM
| ID: wpr-714642
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS: Western guidelines recommend Helicobacter pylori eradication in H. pylori-associated gastric polyps; however, there is no standard guideline in Korea. The aim of this study is to assess the effect of H. pylori eradication on the regression of gastric hyperplastic polyps in National Cancer Screening Cohort, representative of general population. METHODS: Among participants in National Cancer Screening Program, subjects who had H. pylori positive gastric hyperplastic polyps less than 10 mm and underwent follow-up endoscopy and H. pylori testing were enrolled. The effect of H. pylori eradication on hyperplastic gastric polyps was estimated using odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: A total of 183 H. pylori infected subjects with hyperplastic polyp at baseline underwent follow-up endoscopy and H. pylori test after mean of 2.2 years. Successful H. pylori eradication markedly induced the disappearance of hyperplastic polyps comparing to non-eradication group (83.7% vs. 34.1%, p = 0.001). Successful eradication increased the possibility of disappearance of hyperplastic polyps (adjusted OR, 5.56; 95% CI, 2.63 to 11.11). Polyp size was inversely related with the disappearance of hyperplastic polyps (adjusted OR, 59; 95% CI, 0.48 to 0.71). CONCLUSIONS: Eradication of H. pylori infection may induce disappearance of gastric hyperplastic polyps in National Cancer Screening Cohort.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Pólipos
/
Razão de Chances
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Estudos de Coortes
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Seguimentos
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Helicobacter pylori
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Helicobacter
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Endoscopia
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Detecção Precoce de Câncer
/
Coreia (Geográfico)
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
País/Região como assunto:
Asia
Idioma:
En
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2018
Tipo de documento:
Article