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Early Valuable Risk Stratification with Hemoglobin Level and Neutrophil to Lymphocyte Ratio in Patients with Non-ST-Elevation Myocardial Infarction Having an Early Invasive Strategy
Journal of Lipid and Atherosclerosis ; : 50-61, 2018.
Artigo em Inglês | WPRIM | ID: wpr-714784
ABSTRACT

OBJECTIVE:

The complete blood count is the most widely available laboratory data in the early in-hospital period after acute myocardial infarction. We assessed the clinical utility of the combined use of hemoglobin (Hb) level and neutrophil to lymphocyte ratio (N/L) for early risk stratification in patients with non-ST-elevation myocardial infarction (STEMI).

METHODS:

We analyzed 6,157 consecutive patients with non-STEMI (65±12.4 years, male 69%) were included in the final analysis. Patients were categorized into 3 groups by using the median value of N/L (4.42) and the presence of anemia (Hb <13 mg/dL in men and <12 mg/dL in women) group I, low N/L & no anemia (n=3,170); group II, no group I or III (n=2,168); group III, high N/L & anemia (n=819).

RESULTS:

There were significant differences on clinical outcomes during 180-day follow-up among 3 groups. The prognostic discriminatory capacity of the combined use of Hb level and N/L was also significant in high-risk subgroups, such as patients with a renal dysfunction, multivessel coronary disease, low ejection fraction, and even in those having higher mortality risk based on the thrombolysis in myocardial infarction risk score. In a multi-variate logistic regression, after adjusting for multiple covariates, group III had higher incidence of major adverse cardiac events at 180-day (hazard ratio, 2.4; 95% confidence interval, 1.5–4.0;p≤0.001) compared with group I.

CONCLUSIONS:

The combined use of Hb level and N/L provides valuable timely information for early risk stratification in patients with non-STEMI.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Contagem de Células Sanguíneas / Linfócitos / Modelos Logísticos / Incidência / Seguimentos / Mortalidade / Doença das Coronárias / Anemia / Infarto do Miocárdio Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos / Masculino Idioma: Inglês Revista: Journal of Lipid and Atherosclerosis Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Contagem de Células Sanguíneas / Linfócitos / Modelos Logísticos / Incidência / Seguimentos / Mortalidade / Doença das Coronárias / Anemia / Infarto do Miocárdio Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos / Masculino Idioma: Inglês Revista: Journal of Lipid and Atherosclerosis Ano de publicação: 2018 Tipo de documento: Artigo