Sepsis and Meningitis due to Listeria Monocytogenes
Yonsei Medical Journal
;
: 433-439, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-71497
ABSTRACT
PURPOSE:
This study focused on the effect of immuno-compromising conditions on the clinical presentation of severe listerial infection. PATIENTS ANDMETHODS:
Nine human listeriosis cases seen from 1991-2002 were reviewed. All adult patients, from whose blood, peritoneal fluid or cerebrospinal fluid (CSF) the L. monocytogenes was isolated, were included in this retrospective study.RESULTS:
Listeriosis presented as primary sepsis with positive blood cultures in 5 cases and meningitis with positive CSF cultures in 4 cases. All of these patients had at least one underlying disease, most commonly, hematologic malignancy, diabetes mellitus, amyloidosis and hepatic cirrhosis; 55.6% had received immunosuppressive or corticosteroid therapy within a week before the onset of listeriosis. The patients were adults with a mean age of 60 years. Fever, night sweats, chills and lethargy were the most common symptoms; high temperature (> 38 degrees C), tachycardia, meningeal signs and poor conditions in general were the most common findings on admission. The mortality rate was 33.3% and was strictly associated with the severity of the underlying disease. Mortality differences were significant between sepsis (20%) and meningitis (50%) patients.CONCLUSION:
Listeriosis as an uncommon infection in our region and that immuno- suppressive therapy is an important pre-disposing factor of listeriosis. Sepsis and meningitis were more common in this group of patients and had the highest case-fatality rate for food-borne illnesses.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Líquido Ascítico
/
Estudos Retrospectivos
/
Resultado do Tratamento
/
Meningites Bacterianas
/
Corticosteroides
/
Sepse
/
Imunossupressores
/
Listeriose
/
Listeria monocytogenes
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
2007
Tipo de documento:
Artigo
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