Incidence Rate of Injection-Site Granulomas Resulting from the Administration of Luteinizing Hormone-Releasing Hormone Analogues for the Treatment of Prostatic Cancer
Yonsei Medical Journal
;
: 421-424, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-71499
ABSTRACT
PURPOSE:
Granulomas resulting from the administration of luteinizing hormone-releasing hormone analogues (LH-RH analogues) are thought to be very rare. We report on our clinical experience with injection-site granulomas that result from the administration of LH-RH analogues, and we evaluate the incidence rate of these granulomas. MATERIALS ANDMETHODS:
We used the clinical records of 118 patients who were administered LH-RH analogues in 2005. We describe the clinical data of patients who experienced injection-site granulomas and evaluated the incidence rate.RESULTS:
Five patients demonstrated injection-site granulomas due to LH-RH analogue administration. The incidence rate was 4.2% (5 of 118 patients). Most of the granulomas occurred after the first or second administration of 11.25mg of leuprorelin acetate.CONCLUSION:
The occurrence of granulomas resulting from the administration of LH-RH analogues was thought to be very rare. Our study, however, revealed a higher incidence rate than expected, especially for leuprorelin acetate.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias da Próstata
/
Antígenos de Diferenciação Mielomonocítica
/
Antígenos CD
/
Hormônio Liberador de Gonadotropina
/
Leuprolida
/
Gosserrelina
/
Complexo CD3
/
Antineoplásicos Hormonais
/
Granuloma
/
Injeções Subcutâneas
Tipo de estudo:
Estudo de incidência
Limite:
Idoso
/
Aged80
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
2007
Tipo de documento:
Artigo
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