Adjuvant Chemotherapy Versus Chemoradiation for Patients with Resected Pancreatic Adenocarcinoma: A Single-Center Retrospective Study / 대한췌담도학회지
Korean Journal of Pancreas and Biliary Tract
;
: 108-115, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-715804
ABSTRACT
BACKGROUND/AIMS:
This study aimed to compare the outcomes of patients who received systemic chemotherapy or chemoradiotherapy as adjuvant therapies following pancreatic adenocarcinoma resection.METHODS:
We reviewed the medical records of 40 patients with locoregional pancreatic adenocarcinoma who underwent tumor resection at Pusan National University Hospital between 2008 and 2012.RESULTS:
Twenty-nine patients were treated with adjuvant therapy comprising either systemic chemotherapy or chemoradiotherapy after curative-intent surgery. Adjuvant therapy (p=0.025) and complete resection (p=0.043) were associated with longer overall survival. There was no significant difference between chemotherapy and chemoradiotherapy in terms of extending overall survival; however, patients who received chemotherapy had significantly higher survival rates than those who received no adjuvant therapy at all (p=0.012).CONCLUSIONS:
Adjuvant therapies improve the prognoses of patients with resected pancreatic adenocarcinoma; moreover, chemotherapy produced more favorable outcomes than chemoradiotherapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Pancreáticas
/
Prognóstico
/
Adenocarcinoma
/
Prontuários Médicos
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Quimioterapia Adjuvante
/
Tratamento Farmacológico
/
Quimiorradioterapia
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pancreas and Biliary Tract
Ano de publicação:
2018
Tipo de documento:
Artigo
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