Hyponatremia in Liver Cirrhosis / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 74-78, 2018.
Artigo
em Coreano
| WPRIM
| ID: wpr-716131
ABSTRACT
Hyponatremia is a commonly observed complication that is related to hypoalbuminemia and portal hypertension in patients with advanced liver cirrhosis. Hyponatremia in patients with liver cirrhosis is mostly dilutional hyponatremia and is defined when the serum sodium concentration is below 130 meq/L. The risk of complications increases significantly in cirrhotic patients with hyponatremia, which includes spontaneous bacterial peritonitis, hepatorenal syndrome, and hepatic encephalopathy. In addition, hyponatremia is associated with increased morbidity and mortality in patients with cirrhosis, and is an important prognostic factor before and after liver transplantation. The conventional therapies of hyponatremia are albumin infusion, fluid restriction and loop diuretics, but these are frequently ineffective. This review investigates the pathophysiology and various therapeutic modalities, including selective vasopressin receptor antagonists, for the management of hyponatremia in patients with liver cirrhosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peritonite
/
Sódio
/
Fibrose
/
Síndrome Hepatorrenal
/
Encefalopatia Hepática
/
Mortalidade
/
Transplante de Fígado
/
Hipoalbuminemia
/
Inibidores de Simportadores de Cloreto de Sódio e Potássio
/
Antagonistas dos Receptores de Hormônios Antidiuréticos
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2018
Tipo de documento:
Artigo
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