Treatment efficacy of high dose progestin in young women with early stage of endometrial carcinoma / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 486-493, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-71618
ABSTRACT
OBJECTIVE:
The aim of this study is to investigate the effectiveness of high dose progestins in young patients with early stage of endometrial cancer.METHODS:
Between April 1998 and December 2005, 10 women with early stage of endometrial carcinoma were treated with high dose progestins as primary therapy for the purpose of saving fertility.RESULTS:
They took 80~160 mg of megestrol acetate or 500~1,000 mg of medroxyprogesterone acetate per day, and then followed up with the endometrial curettages. Seven patients (70.0%) responded to the treatment. Three patients didn't respond and so underwent hysterectomy as definite treatment. Four patients were able to become pregnant after completing treatment. No patients died of their disease.CONCLUSION:
The majority of patients with well-differentiated endometrial adenocarcinoma who underwent conservative treatment with a progestational agent responded to the treatment. High-dose progestin therapy can be used as primary therapy in selected young women with early stage of endometrial carcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Progestinas
/
Adenocarcinoma
/
Resultado do Tratamento
/
Neoplasias do Endométrio
/
Acetato de Medroxiprogesterona
/
Acetato de Megestrol
/
Curetagem
/
Fertilidade
/
Histerectomia
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2007
Tipo de documento:
Artigo
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