The effect of tamoxifen therapy on the endometrium and ovarian cyst formation in patients with breast cancer
Obstetrics & Gynecology Science
;
: 615-620, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-716660
ABSTRACT
OBJECTIVE:
To evaluate the effect of tamoxifen on female reproductive organs in women with breast cancer.METHODS:
We retrospectively reviewed the medical records of 309 women with breast cancer who were currently receiving tamoxifen and undergoing regular gynecological examination.RESULTS:
We evaluated 92 pre- and 217 postmenopausal women. The prevalence of endometrial thickening was 12% in the pre- and 10.6% in the postmenopausal group. An endometrial biopsy was performed in 43 women and confirmed endometrial cancer in 1, endometrial polyps in 14, and endometrial hyperplasia in 4 women. Transvaginal ultrasonography showed 25 cases of newly developed ovarian cysts. Most ovarian cysts had disappeared during follow-up.CONCLUSION:
Tamoxifen use in women with breast cancer causes few complications and is considered safe for female reproductive organs in case of regular gynecological examination.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cistos Ovarianos
/
Ovário
/
Pólipos
/
Tamoxifeno
/
Biópsia
/
Mama
/
Neoplasias da Mama
/
Prontuários Médicos
/
Prevalência
/
Estudos Retrospectivos
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Obstetrics & Gynecology Science
Ano de publicação:
2018
Tipo de documento:
Artigo
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