Dehydroepiandrosterone and Erectile Function: A Review
The World Journal of Men's Health
;
: 183-191, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-716917
ABSTRACT
To review the contemporary knowledge regarding the dehydroepiandrosterone and erectile function. Medline was reviewed for English-language journal articles spanning the time between January 1990 and December 2017, using the terms ‘erectile function’, ‘dehydroepiandrosterone’. We used original articles and review articles that found to be relevant to the purpose of this review. Criteria included all pertinent review articles, randomized controlled trials with tight methodological design, cohort studies and retrospective analyses. We also manually revised references from selected articles. Several interesting studies have addressed the age-related decline in dehydroepiandrosterone levels with many age-related phenomena or deterioration in various physiological functions. Particularly, aging; neurological functions including decreased well-being, cognition, and memory; increased depression, decreased bone mineral density, obesity, diabetes, increased cardiovascular morbidity, erectile dysfunction (ED), and decreased libido. Supporting this result, some trials of dehydroepiandrosterone supplementation in healthy, middle-aged, and elderly subjects have reported improvements in different aspects of well-being. Several studies had demonstrated that dehydroepiandrosterone level is declined as a part of aging. Large-scale well-designed prospective studies are warranted to better define indications and therapeutic implications of dehydroepiandrosterone in men with ED.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Testosterona
/
Envelhecimento
/
Densidade Óssea
/
Estudos Prospectivos
/
Estudos Retrospectivos
/
Estudos de Coortes
/
Desidroepiandrosterona
/
Cognição
/
Depressão
/
Disfunção Erétil
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
The World Journal of Men's Health
Ano de publicação:
2018
Tipo de documento:
Artigo
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