Ultrasound-Guided Botulinum Toxin Injection with Factor VIII Administration for Post Stroke Spasticity in a Hemophilia A Patient
Brain & Neurorehabilitation
;
: e20-2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-716991
ABSTRACT
Chemodenervation with botulinum toxin (BTX) has been recommended for focal spasticity. BTX injection should be performed with caution in patients with bleeding disorders and/or receiving anticoagulation therapy. We present a case of BTX injection for post-stroke spasticity in a patient with hemophilia A who could not take oral spasmolytics due to chronic hepatitis C. To minimize the bleeding risk, we replaced factor VIII intravenously in accordance with the World Federation of Hemophilia guidelines for minor surgery. FVIII (3,000 IU) was administered 15 minutes before BTX injection. One day later, 2,000 IU was administered, and 2 days later, another 2,000 IU was administered. We performed the real-time Ultrasound-guided BTX injection three times, then spasticity and upper extremity function improved without adverse events. BTX injection can be considered as a treatment option for spasticity among patients with hemophilia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Parassimpatolíticos
/
Procedimentos Cirúrgicos Menores
/
Toxinas Botulínicas
/
Fator VIII
/
Ultrassonografia
/
Hepatite C Crônica
/
Acidente Vascular Cerebral
/
Extremidade Superior
/
Hemofilia A
/
Hemorragia
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
Limite:
Humanos
Idioma:
Inglês
Revista:
Brain & Neurorehabilitation
Ano de publicação:
2018
Tipo de documento:
Artigo
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