Fecal Microbiota Transplantation to Patients with Refractory Very Early Onset Ulcerative Colitis / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition
;
: 355-360, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-717798
ABSTRACT
Recently, fecal microbiota transplantation (FMT) has been attracting attention as a possible medical treatment of ulcerative colitis (UC). A randomized controlled trial of FMT for children with UC is currently underway. Therapeutic effects of FMT for adults with UC remain controversial. We report two cases of early-onset UC in children. A patient was diagnosed with UC at age 1-year 9-month and underwent FMT at age 2-year 3-month. He attained clinical remission for three weeks after FMT, but then relapsed at four weeks, ultimately undergoing a total colectomy. Another child was diagnosed with UC at 2-year 10-month and she underwent FMT at age 5 years. She has remained in clinical remission following FMT for 24 months and her UC has been maintained without complications with tacrolimus and azathioprine. We report that FMT for early-onset UC appears to be safe and potentially effective.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Azatioprina
/
Úlcera
/
Colite Ulcerativa
/
Tacrolimo
/
Colectomia
/
Usos Terapêuticos
/
Transplante de Microbiota Fecal
/
Microbioma Gastrointestinal
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Adulto
/
Criança
/
Humanos
Idioma:
Inglês
Revista:
Pediatric Gastroenterology, Hepatology & Nutrition
Ano de publicação:
2018
Tipo de documento:
Artigo
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