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Promotion of excisional wound repair by a menstrual blood-derived stem cell-seeded decellularized human amniotic membrane
Biomedical Engineering Letters ; (4): 393-398, 2018.
Artigo em Inglês | WPRIM | ID: wpr-717984
ABSTRACT
This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via decellularized human amniotic membrane (DAM), for the promotion of skin excisional wound repair. The DAM was seeded with MenSCs at the density of 3 × 10⁴ cells/cm² and implanted onto a rat's 1.50 × 1.50 cm² full-thickness excisional wound defect. The results of wound closure and histopathological examinations demonstrated that the MenSC-seeded DAM could significantly improve the wound healing compared with DAM-treatment. All in all, our data indicated that the MenSCs can be a potential source for cell-based therapies to regenerate skin injuries.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Células-Tronco / Cicatrização / Ferimentos e Lesões / Âmnio Limite: Humanos Idioma: Inglês Revista: Biomedical Engineering Letters Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Células-Tronco / Cicatrização / Ferimentos e Lesões / Âmnio Limite: Humanos Idioma: Inglês Revista: Biomedical Engineering Letters Ano de publicação: 2018 Tipo de documento: Artigo