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Factors Associated with Lung Function Recovery at the First Year after Lung Transplantation
Yonsei Medical Journal ; : 1088-1095, 2018.
Artigo em Inglês | WPRIM | ID: wpr-718031
ABSTRACT

PURPOSE:

Post-operative pulmonary function is an important prognostic factor for lung transplantation. The purpose of this study was to identify factors affecting recovery of forced expiratory volume in 1 second (FEV1) at the first year after lung transplantation. MATERIALS AND

METHODS:

We retrospectively reviewed the medical records of lung transplantation patients between October 2012 and June 2016. Patients who survived for longer than one year and who underwent pulmonary function test at the first year of lung transplantation were enrolled. Patients were divided into two groups according to whether they recovered to a normal range of FEV1 (FEV1 ≥80% of predicted value vs. < 80%). We compared the two groups and analyzed factors associated with lung function recovery.

RESULTS:

Fifty-eight patients were enrolled in this study 28 patients (48%) recovered to a FEV1 ≥80% of the predicted value, whereas 30 patients (52%) did not. Younger recipients [odds ratio (OR), 0.92; 95% confidence interval (CI), 0.87–0.98; p=0.010], longer duration of mechanical ventilator use after surgery (OR, 1.14; 95% CI, 1.03–1.26; p=0.015), and high-grade primary graft dysfunction (OR, 8.08; 95% CI, 1.67–39.18; p=0.009) were identified as independent risk factors associated with a lack of full recovery of lung function at 1 year after lung transplantation.

CONCLUSION:

Immediate postoperative status may be associated with recovery of lung function after lung transplantation.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Valores de Referência / Testes de Função Respiratória / Ventiladores Mecânicos / Volume Expiratório Forçado / Prontuários Médicos / Estudos Retrospectivos / Fatores de Risco / Transplante de Pulmão / Recuperação de Função Fisiológica / Disfunção Primária do Enxerto Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Inglês Revista: Yonsei Medical Journal Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Valores de Referência / Testes de Função Respiratória / Ventiladores Mecânicos / Volume Expiratório Forçado / Prontuários Médicos / Estudos Retrospectivos / Fatores de Risco / Transplante de Pulmão / Recuperação de Função Fisiológica / Disfunção Primária do Enxerto Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Inglês Revista: Yonsei Medical Journal Ano de publicação: 2018 Tipo de documento: Artigo