Anesthetic and Perioperative Management of Patient with Paroxysmal Nocturnal Hemoglobinuria / 계명의대학술지
Keimyung Medical Journal
;
: 92-96, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-718506
ABSTRACT
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal hematopoietic stem cell disorder. Surgery, anesthesia, infection, trauma, and pregnancy can exacerbate hemolysis and thrombotic risk by increasing complement activity. However, perioperative treatment of eculizumab can reduce risk of hemolytic event by surgical stress. Here, we present the perioperative clinical course and adequate anesthetic management of PNH complicated by spine surgery under general anesthesia. We also describe a possible role of eculizumab for PNH patients with anticipated high risks.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Coluna Vertebral
/
Trombose
/
Proteínas do Sistema Complemento
/
Células-Tronco Hematopoéticas
/
Hemoglobinúria
/
Hemoglobinúria Paroxística
/
Hemólise
/
Anestesia
/
Anestesia Geral
Limite:
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Keimyung Medical Journal
Ano de publicação:
2018
Tipo de documento:
Artigo
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