Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy for Treatment of Calcium Channel Blockers, Angiotensin II Receptor Blockers, and Metformin Overdose
Journal of The Korean Society of Clinical Toxicology
;
: 165-171, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-718673
ABSTRACT
An overdose of antihypertensive agents, such calcium channel blockers (CCBs) and angiotensin II receptor blocker (ARBs), and the antihyperglycemic agent, metformin, leads to hypotension and lactic acidosis, respectively. A 40-year-old hypertensive and diabetic man with hyperlipidemia and a weight of 110 kg presented to the emergency room with vomiting, dizziness, and hypotension following an attempted drug overdose suicide with combined CCBs, ARBs, 3-hydroxy-3-methylglutaryl-coemzyme A reductase inhibitors, and metformins. A conventional medical treatment initially administered proved ineffective. The treatment was then changed to simultaneous extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT), which was effective. This shows that simultaneous ECMO and CRRT can be an effective treatment protocol in cases of ineffective conventional medical therapy for hypotension and lactic acidosis due to an overdose of antihypertensive agents and metformin, respectively.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxirredutases
/
Suicídio
/
Vômito
/
Acidose Láctica
/
Receptores de Angiotensina
/
Bloqueadores dos Canais de Cálcio
/
Canais de Cálcio
/
Oxigenação por Membrana Extracorpórea
/
Protocolos Clínicos
/
Cálcio
Tipo de estudo:
Guia de Prática Clínica
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Journal of The Korean Society of Clinical Toxicology
Ano de publicação:
2018
Tipo de documento:
Artigo
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