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Pharmaceutical Drug Poisoning after Deregulation of Over the Counter Drug Sales: Emergency Department Based In-depth Injury Surveillance
Journal of The Korean Society of Clinical Toxicology ; : 141-148, 2018.
Artigo em Inglês | WPRIM | ID: wpr-718677
ABSTRACT

PURPOSE:

The Korean government approved selected nonprescription drugs (Over-The-Counter drug; OTC drug) to be distributed in convenience stores from 15. Nov. 2012. This study examined the changes in the incidence and the clinical outcome of acute pharmaceutical drug poisoning after the deregulation of OTC drug sales.

METHODS:

This study analyzed the data of Emergency Department based Injury In-depth Injury Surveillance (EDIIS), Korea Centers for Disease Control and Prevention, from 2011 to 2014. The following items were examined age, gender, intention, alcohol association, pharmaceutical drugs resulting acute poisoning, the clinical outcomes in emergency department, and the admission rate of intensive care unit (ICU). This is a retrospective cross section observational study.

RESULTS:

A total of 10,162 patients were subject to pharmaceutical drug poisoning. Acute poisoning by acetaminophen and other drugs were 1,015 (10.0%) and 9,147 (90.0%) patients, respectively. After the deregulation of OTC drug sales, acute poisoning by other drugs increased from 4,385 to 4,762 patients but acute poisoning by acetaminophen decreased from 538 to 477 patients (p < 0.05). The rate of admission of acetaminophen poisoning increased from 36.1% (194/538) to 46.8% (223/477). The admission rate to the ICU by acetaminophen poisoning increased from 4.6% (25/538) to 11.3% (54/477) after the deregulation of OTC drug sales (p < 0.05).

CONCLUSION:

Since the deregulation of OTC drugs sales, pharmaceutical drug poisoning has increased but acetaminophen poisoning has decreased. The rate of hospitalization and ICU admission by pharmaceutical drug poisoning with or without acetaminophen has also increased.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Intoxicação / Incidência / Estudos Retrospectivos / Comércio / Intenção / Medicamentos sem Prescrição / Emergências / Serviço Hospitalar de Emergência / Overdose de Drogas / Estudo Observacional Tipo de estudo: Estudo de incidência / Estudo observacional / Estudo prognóstico / Estudo de rastreamento Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Journal of The Korean Society of Clinical Toxicology Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Intoxicação / Incidência / Estudos Retrospectivos / Comércio / Intenção / Medicamentos sem Prescrição / Emergências / Serviço Hospitalar de Emergência / Overdose de Drogas / Estudo Observacional Tipo de estudo: Estudo de incidência / Estudo observacional / Estudo prognóstico / Estudo de rastreamento Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Journal of The Korean Society of Clinical Toxicology Ano de publicação: 2018 Tipo de documento: Artigo