The Effect of Dorzolamide-Timolol and Latanoprost on Redox Cycle in Aqueous Humor of Rabbit
Journal of the Korean Ophthalmological Society
;
: 424-428, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-71885
ABSTRACT
PURPOSE:
To evaluate the effect of dorzolamide-timolol and latanoprost on redox cycle of superoxide dismutase (SOD) and ascorbic acid in the aqueous humor of the rabbit.METHODS:
Group 1 (20 eyes of 10 rabbits) was instilled with dorzolamide-timolol in the right eye and Group 2 (20 eyes of 10 rabbits) was instilled with latanoprost in the same manner. Four weeks after instillation, SOD activity and ascorbic acid concentration were analyzed.RESULTS:
In Group 1, SOD activity and ascorbic acid concentration of the right eye and left eye were 15.7% and 19.3% (p=0.27), 2.7 pM and 2.6 pM (p=0.47), respectively. In Group 2, SOD activity and ascorbic acid concentration of the right and left eye were 22.3% and 27.6% (p=0.14), 2.3 pM and 2.1 pM (p=0.89), respectively.CONCLUSIONS:
There was no significant difference of SOD activity and ascorbic acid concentration between both eyes in Group 1 and 2.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxirredução
/
Humor Aquoso
/
Prostaglandinas F Sintéticas
/
Ácido Ascórbico
/
Superóxido Dismutase
/
Olho
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2009
Tipo de documento:
Artigo
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