Nonalcoholic fatty liver disease in obese and nonobese pediatric patients / 소아과
Korean Journal of Pediatrics
;
: 30-35, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-719431
ABSTRACT
PURPOSE:
Obesity is risk factor for nonalcoholic fatty liver disease (NAFLD). However, nonobese patients are also increasingly susceptible to NAFLD. The aim of this study was to compare the clinical characteristics of obese and nonobese pediatric patients with NAFLD.METHODS:
We retrospectively studied 68 patients who were diagnosed with NAFLD between January 2010 and October 2016 at 10–18 years of age. Body mass index ≥95th percentile for age and sex was defined as obesity. Abdominal ultrasonography and laboratory, anthropometrics measurements were evaluated.RESULTS:
Among the 68, 26 (38.2%) were nonobese patients. The ratio of male to female was 5.81, and the median age at diagnosis was 13 years (range, 10–17 years). Significant higher triglyceride (223.0 mg/dL vs. 145.9 mg/dL, P=0.047) and total cholesterol levels (211.6 mg/dL vs. 173.2 mg/dL, P=0.011) were shown in nonobese than obese patients. High-density lipoprotein cholesterol level 200mg/dL (HR, 5.6; 95% CI, 1.23–15.31; P=0.038) and abdominal obesity (HR, 2.53; 95% CI, 1.22–4.68; P=0.013) were significant risk factors for NAFLD in nonobese patients.CONCLUSION:
Nonobese patients present a substantial proportion of pediatric NAFLD cases. Significant abnormal lipid concentrations were found in nonobese and abdominal obesity was important risk factor for nonobese NAFLD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Triglicerídeos
/
Índice de Massa Corporal
/
Colesterol
/
Estudos Retrospectivos
/
Fatores de Risco
/
Ultrassonografia
/
Diagnóstico
/
Obesidade Abdominal
/
Obesidade Infantil
/
Hepatopatia Gordurosa não Alcoólica
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2019
Tipo de documento:
Artigo
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