Trisomy 9, As a Sole Chromosomal Aberration in Refractory Anemia with Excess Blasts-II / 대한진단검사의학회지

ABSTRACT

Refractory anemia with excess blasts (RAEB), the most commom type of myelodysplastic syndrome (MDS), accounts for 40-60% of all patients newly diagnosed with MDS. Various clonal cyto-genetic abnormalities are found in 30 to 50% of the cases. But, trisomy 9 as a sole chromosomal aberration is not common, which was observed in our patient. We report a 65-year-old female with trisomy 9. She was diagnosed with RAEB-II four years ago, and she had no evidence of progression to acute leukemia without therapy.