Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March
Allergy, Asthma & Immunology Research
;
: 4-15, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-719516
ABSTRACT
The Atopic march denotes the progression from atopic dermatitis (AD) to the development of other allergic disorders such as immunoglobulin (Ig) E-mediated food allergy, allergic rhinitis and asthma in later childhood. There is increasing evidence from prospective birth cohort studies that early-onset AD is a risk factor for other allergic diseases or is found in strong association with them. Animal studies now provide mechanistic insights into the pathways that may be responsible for triggering the progression from the skin barrier dysfunction seen in AD to epicutaneous sensitization, food allergy and allergic airway disorders. Recent large randomized controlled trials have demonstrated the efficacy of early interventions targeted at AD and food allergy prevention. These show great promise for research into future strategies aimed at prevention of the atopic march.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Asma
/
Pele
/
Imunoglobulinas
/
Estudos Prospectivos
/
Fatores de Risco
/
Estudos de Coortes
/
Intervenção Educacional Precoce
/
Parto
/
Dermatite Atópica
/
Rinite Alérgica
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
Allergy, Asthma & Immunology Research
Ano de publicação:
2019
Tipo de documento:
Artigo
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