A case of transfusion-related acute lung injury induced by anti-human leukocyte antigen antibodies in acute leukemia
Korean Journal of Hematology
;
: 302-306, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-720305
ABSTRACT
Transfusion-related acute lung injury (TRALI) is a noncardiogenic pulmonary edema that occurs during or within 6 hours after transfusion. Risk factors for TRALI, which is relatively common in critically ill patients, include recent surgery, hematologic malignancy, and sepsis. Here, we report a case of TRALI induced by anti-human leukocyte antigen (anti-HLA) class II antibodies (HLA-DR) occurring after transfusion of platelet concentrates in a patient with acute leukemia. Although most patients with TRALI show improvement within 48-96 hours, our patient's condition rapidly worsened, and he did not respond to supportive treatment. TRALI is a relatively common and serious adverse transfusion reaction that requires prompt diagnosis and management.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Edema Pulmonar
/
Incompatibilidade de Grupos Sanguíneos
/
Plaquetas
/
Leucemia
/
Fatores de Risco
/
Estado Terminal
/
Sepse
/
Neoplasias Hematológicas
/
Lesão Pulmonar Aguda
/
Leucócitos
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Hematology
Ano de publicação:
2012
Tipo de documento:
Artigo
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