Long-term survival in a patient with acute promyelocytic leukemia with isolated meningeal relapse
Korean Journal of Hematology
;
: 208-210, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-720389
ABSTRACT
The meningeal involvement is rare in acute promyelocytic leukemia. We experienced a 39-year-old woman who achieved complete remission with all-trans retinoic acid, idarubicin and cytarabine therapy. Several months later, she complained of non-specific headache. Her complete blood cell count was normal, but magnetic resonance image of brain revealed focal meningeal enhancement and cerebrospinal fluid showed leukemic promyelocytes and PML/RARA rearrangement. Bone marrow study showed hematologic, cytogenetic and molecular remission. She was treated with intrathecal and systemic chemotherapy and whole brain radiotherapy. The patient has survived for 68 months since the last systemic chemotherapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Tretinoína
/
Contagem de Células Sanguíneas
/
Medula Óssea
/
Encéfalo
/
Espectroscopia de Ressonância Magnética
/
Idarubicina
/
Leucemia Promielocítica Aguda
/
Citarabina
/
Citogenética
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Hematology
Ano de publicação:
2010
Tipo de documento:
Artigo
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