Generalized Primary Amyloid Lymphadenopathy
Korean Journal of Hematology
;
: 320-324, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-721041
ABSTRACT
Systemic amyloidosis is a disease that displays deposition of insoluble polymeric protein fibrils in tissues and organs. We report here on a case of a 64-year-old woman who initially presented with multiple enlarged lymph nodes. Computed tomography showed multiple enlarged lymph nodes in the mediastinal, lower cervical, supraclavicular, axillary and abdominal areas. Excision biopsy of the cervical lymph nodes and the subsequent histopathology showed amorphous eosinophilic material deposits, and these revealed apple-green birefringence on a polarizing microscopic examination on the Congo-red stained slide. The patient was diagnosed with amyloidosis and she received chemotherapy consisting of melphalan and dexamethasone. During chemotherapy, she was diagnosed with breast cancer. After modified unilateral radical mastectomy, the dexamethasone was restarted and this therapy resulted in stable disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polímeros
/
Biópsia
/
Birrefringência
/
Neoplasias da Mama
/
Dexametasona
/
Mastectomia Radical
/
Eosinófilos
/
Amiloide
/
Amiloidose
/
Linfonodos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Hematology
Ano de publicação:
2009
Tipo de documento:
Artigo
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