Analysis of survival data in thalassemia patients in Shiraz, Iran / 한국역학회지
Epidemiology and Health
;
: e2015031-2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-721218
ABSTRACT
OBJECTIVES:
The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.METHODS:
This retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.RESULTS:
Overall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.CONCLUSIONS:
Sociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Talassemia
/
Comorbidade
/
Prontuários Médicos
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Estatística como Assunto
/
Estudos de Coortes
/
Mortalidade
/
Pessoal de Saúde
/
Estado Civil
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Epidemiology and Health
Ano de publicação:
2015
Tipo de documento:
Artigo
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