Analysis on the Etiology and Prognostic Factors of Community-Acquired Bacteremia in a Community-Based Tertiary Hospital / 감염과화학요법
Infection and Chemotherapy
;
: 255-264, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-721438
ABSTRACT
BACKGROUND:
We conducted this study to describe the epidemiology of community-acquired bacteremia and identify its prognostic factors. MATERIALS ANDMETHODS:
All patients admitted to a community-based tertiary hospital with community-acquired bacteremia from June 2002 to May 2004 were included and analyzed retrospectively.RESULTS:
During the study period, clinically significant community-acquired bacteremia occurred in 223 patients with the frequency of 5.3 patients per 1,000 patient-admission. The commonly isolated organisms were E. coli (47.1%), K. pneumoniae (13.0%), S. aureus (8.1%), and S. pneumoniae (4.5 %). The leading source of bacteremia were urinary tract infection (34.5%), intraabdominal infection (33.6%), primary bacteremia (10.3%), and skin & soft tissue infection (8.1%). The overall mortality was 17%. S. aureus (34.8%) and K. pneumoniae (30.4%) were two major organisms of primary bacteremia with high case fatality of 50% and 28.6%, respectively. Univariate analysis showed that the followings were associated with significant increase in mortality male patient; S. aureus and other streptococci bacteremia; increasing APACHE II score; definite diagnosis after 3 days of admission; inappropriate antibiotics therapy within 24 hours of admission; emergency room; admission to ICU. The independent predictors of mortality were male patient (RR 3.02, P=0.031), increasing APACHE II score (RR 1.12, P=0.011), and admission to ICU (RR 9.73, P<0.001).CONCLUSION:
Rapid definite diagnosis and prompt administration of appropriate antibiotics according to the local epidemiologic pattern are the most important controllable factors for the better outcome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Prognóstico
/
Pele
/
Infecções Urinárias
/
Epidemiologia
/
Estudos Retrospectivos
/
Mortalidade
/
Bacteriemia
/
Infecções dos Tecidos Moles
/
APACHE
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Infection and Chemotherapy
Ano de publicação:
2005
Tipo de documento:
Artigo
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