Disseminated Aspergillosis following Allogeneic Hematopoietic Stem Cell Transplantation in an Acute Leukemic Patient who was Previously Treated for Invasive Aspergillosis / 감염과화학요법
Infection and Chemotherapy
;
: 221-225, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-721969
ABSTRACT
Invasive aspergillosis has been increasing as the number of severe immunocompromised hosts rises. Particularly, in allogeneic hematopoietic stem cell transplantation (HSCT) recipients, incidence of invasive aspergillosis ranges from 4 to 10%. Even with appropriate treatment, the prognosis of invasive aspergillosis in allogeneic HSCT recipients remains poor, showing high mortality rate. Herein, we report a case where invasive aspergillosis in a patient with acute myelogeneous leukemia progressed to disseminated aspergillosis after allogeneic HSCT. A 31-year-old woman with acute myelogenous leukemia had invasive aspergillosis after third reinduction chemotherapy. After administering amphotericin B, the patient underwent the wedge resection of lung, and HLA-matched allogeneic HSCT was then conducted. On day 14 of transplantation, the patient died of disseminated aspergillosis, including possible cerebritis and endocarditis despite the amphotericin B therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Aspergilose
/
Células-Tronco Hematopoéticas
/
Leucemia Mieloide Aguda
/
Leucemia
/
Anfotericina B
/
Incidência
/
Mortalidade
/
Hospedeiro Imunocomprometido
/
Transplante de Células-Tronco Hematopoéticas
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Infection and Chemotherapy
Ano de publicação:
2003
Tipo de documento:
Artigo
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