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Two Cases of Candida inconspicua Infection in Neutropenic Patients with Acute Leukemia / 감염과화학요법
Infection and Chemotherapy ; : 164-168, 2006.
Artigo em Inglês | WPRIM | ID: wpr-721979
ABSTRACT
Non-albicans Candida species which are resistant to azole are emerging as important pathogens in patients with hematological malignancies who received antifungal prophylaxis. C. inconspicua is one of rare Candida spp. and resistant to fluconazole and deep infection due to C. inconspicua has not been reported in Korea so far. We reported here two cases of candidemia due to C. inconspicua in neutropenic patients with acute leukemia. C. inconspicua were presumed to be originated from gastrointestinal tract in both cases. The antifungal susceptibility test of C. inconspicua in case 1 showed resistance to fluconazole and itraconazole. Both cases were successfully treated by amphotericin B deoxycholate. Clinicians should keep in mind that non-albicans Candida species would be emerging pathogen in immunocompromised hosts and early recognition and appropriate use of antifungal agents is necessary.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Candida / Leucemia / Fluconazol / Anfotericina B / Hospedeiro Imunocomprometido / Fungemia / Itraconazol / Neoplasias Hematológicas / Danazol / Trato Gastrointestinal Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Infection and Chemotherapy Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Candida / Leucemia / Fluconazol / Anfotericina B / Hospedeiro Imunocomprometido / Fungemia / Itraconazol / Neoplasias Hematológicas / Danazol / Trato Gastrointestinal Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Infection and Chemotherapy Ano de publicação: 2006 Tipo de documento: Artigo