A Case of Kikuchi's disease accompanied by Hemophagocytic Lymphohistiocytosis / 감염과화학요법
Infection and Chemotherapy
;
: 185-188, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-722297
ABSTRACT
Kikuchi's disease usually occurs in young women and is characterized by localized lymphadenitis (mostly cervical) usually associated with fever. It is considered a self-limited disease and most patients recover spontaneously within a few weeks to 6 months without any serious sequelae. However, patients with Kikuchi's disease require a systemic survey and regular follow-up for several years because it may be associated with other diseases such as systemic lupus erythematosus. To our knowledge, there are very few reports of Kikuchi's disease accompanied by hemophagocytic lymphohistiocytosis. Biopsy of a right cervical lymph node in a 35-year-old female who presented with fever and masses in the right cervical region showed necrotizing lymphadenitis and a diagnosis of Kikuchi's disease was reached. She was started on methylprednisolone pulse therapy (500 mg for 3 days) but developed generalized rash and fever. Laboratory data showed pancytopenia, elevation of serum transaminase and ferritin levels. Bone marrow and liver biopsy showed proliferation of histiocytes and Kupffer's cells engulfing lymphocytes, platelets and red blood cells, respectively. We report a case of Kikuchi's disease accompanied by hemophagocytic lymphohistiocytosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pancitopenia
/
Biópsia
/
Medula Óssea
/
Metilprednisolona
/
Linfócitos
/
Seguimentos
/
Linfadenite Histiocítica Necrosante
/
Diagnóstico
/
Eritrócitos
/
Linfo-Histiocitose Hemofagocítica
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Infection and Chemotherapy
Ano de publicação:
2004
Tipo de documento:
Artigo
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