Changes of Plasma Lipids in Stroke Patients

ABSTRACT

OBJECTIVE: To investigate plasma lipid changes in pre- and poststroke patients and to evaluate the difference of these changes between hemorrhagic and ischemic strokes. METHOD: Two hundred thirty five stroke patients who underwent blood tests for health check-up before stroke were included in this study. Lipids profile among blood tests included total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol. These tests were taken again within 48 hours, at 1 week, and 3 months after stroke. Prestroke lipid profile was compared with the control group, which was composed of two hundred forty seven healthy men. RESULTS: The difference between lipid profile of prestroke and within 48 hours after stroke was not statistically significant. Total cholesterol at 1 week after stroke was significantly lower, but its concentration increased at 3 months after. There's no significant changes in triglyceride, low density lipoprotein cholesterol, or high density lipoprotein cholesterol according to time. There was no significant difference in lipid profile between the ischemic and hemorrhagic strokes and no significant changes between the subtypes of ischemic stroke were noted. CONCLUSION: Our results suggest that the lipid profile after stroke is changed, so the lipid profile taken after stroke are not reflect clearly the state of prestroke lipid concentration.