Cerebrovascular and Cardiovascular Changes According to Postural Change in Spinal Cord Injured Patients: Preliminary report
Journal of the Korean Academy of Rehabilitation Medicine
;
: 749-755, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-724007
ABSTRACT
OBJECTIVE:
To investigate the changes of cerebral and cardiovascular hemodynamics in response to postural change in tetraplegics after cervical spinal cord injury.METHOD:
We studied 5 healthy volunteers and 14 cervical cord injured patients with orthostatic hypotension. We continuously monitored heart rate (HR), blood pressure (BP) by volume clamp photoplethysmography, and cerebral blood flow velocity (BFV), pulsatility index (PI) of middle cerebral artery (MCA) by transcranial Doppler sonography at rest and during head-up-tilt (HUT). Tilt table set at 30o initially and then increased gradually 10o every 5 minutes up to 80o.RESULTS:
In the control group, BP and BFV of MCA remained unchanged during HUT. Although a decrease of BFV observed in all patients during both systolic and diastolic phases, the degree of BFV drop during diastolic phase, especially early diastolic phase was much greater than that during systolic phase. The change of BFV of MCA was significantly correlated with that of systemic hemodynamic parameters, especially systolic BP. After rehabilitative therapy for one month, there was no definite evidence of the change in cerebral autoregulation.CONCLUSION:
This study suggests that we can use systemic hemodynamic parameters for predicting changes of cerebral blood flow in response to orthostatic hypotension, but we fail to observe any compensatory mechanism of cerebrovascular system to maintain cerebral blood flow against systemic hemodynamic collapse.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Medula Espinal
/
Traumatismos da Medula Espinal
/
Velocidade do Fluxo Sanguíneo
/
Pressão Sanguínea
/
Fotopletismografia
/
Ultrassonografia Doppler Transcraniana
/
Artéria Cerebral Média
/
Voluntários Saudáveis
/
Frequência Cardíaca
/
Hemodinâmica
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Rehabilitation Medicine
Ano de publicação:
1999
Tipo de documento:
Artigo
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