Electrophysiological Changes after Botulinum Toxin Type A in Children with Cerebral Palsy
Journal of the Korean Academy of Rehabilitation Medicine
;
: 179-184, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-724311
ABSTRACT
OBJECTIVE:
To investigate the electrophysiological changes after botulinum toxin type A injection in children with cerebral palsy.METHOD:
Sixteen children with spastic cerebral palsy enrolled in the study. Botulinum toxin type A (Dysport(R)) was injected into gastrocnemius muscles. Electrophysiological assessments included the compound motor action potential of the tibial nerve, the sensory nerve action potential of the sural nerve, the H-reflex and the T-reflex before injection, and at 2 weeks and 4 weeks after the injection. Modified Ashworth scale was used to evaluate spasticity before, 2 weeks and 4 weeks after the injection.RESULTS:
Modified Ashworth scale of the ankle decreased at 2 weeks and 4 weeks after injection. The amplitude of the H-reflex and H(max)/M(max) ratio decreased significantly at 4 weeks. The amplitude of the T-reflex decreased at 2 weeks and 4 weeks. The correlation between changes in modified Ashworth scale of the ankle and the changes in electrophysiological parameters at 4 weeks after injection were not significant.CONCLUSION:
The change in T-reflex is faster than the change of H-reflex and H(max)/M(max) ratio after botulinum toxin A injection in children with cerebral palsy. Electrophysiological tests could quantify the change in spasticity after botulinum toxin injection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Compostos Orgânicos
/
Nervo Sural
/
Nervo Tibial
/
Toxinas Botulínicas
/
Potenciais de Ação
/
Paralisia Cerebral
/
Toxinas Botulínicas Tipo A
/
Reflexo H
/
Tornozelo
/
Espasticidade Muscular
Limite:
Animais
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Rehabilitation Medicine
Ano de publicação:
2010
Tipo de documento:
Artigo
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