Pain Relief Effect of Calcitonin Injection in Ovariectomized Rats
Journal of the Korean Academy of Rehabilitation Medicine
;
: 587-590, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-724527
ABSTRACT
OBJECTIVE:
To confirm the effect of calcitonin injection relieving pain in ovariectomized rats.METHOD:
Thirty five Sprague-Dawley rats were randomly divided into five groups (high dose calcitonin group (112 U/ Kg), low dose calcitonin group (56 U/Kg), free calcitonin group, ovariectomy group, control group). To assess the pain in ovariectomized rats, the tail of rats were dived in waters of 50+/-1degrees C. Then the tail withdrawal time was measured (tail withdrawal test). The tail withdrawal test was performed in once a week for eight weeks.RESULTS:
1. At seven and eight weeks after injection, the tail withdrawal time of high and low dose calcitonin group compared with that of ovariectomy group were significantly prolonged (p<0.05). 2. At eight weeks after injection, the tail withdrawal time of free calcitonin group compared with that of ovariectomy group was significantly prolonged (p<0.05).CONCLUSION:
The effect of calcitonin injection relieving pain in ovariectomized rats was found.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cauda
/
Calcitonina
/
Água
/
Ovariectomia
/
Grupos Controle
/
Ratos Sprague-Dawley
Limite:
Animais
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Rehabilitation Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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