A Review of Brain Magnetic Resonance Imaging Correlates of Successful Cognitive Aging
Journal of the Korean Society of Biological Psychiatry
;
: 1-13, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-724998
ABSTRACT
Normal aging causes changes in the brain volume, connection, function and cognition. The brain changes with increases in age and difference of gender varies at all levels. Studies about normal brain aging using various brain magnetic resonance imaging (MRI) variables such as gray and white matter structural imaging, proton spectroscopy, apparent diffusion coefficient, diffusion tensor imaging and functional MRI are reviewed. Total volume of brain increases after birth but decreases after 9 years old. During adulthood, total volume of brain is relatively stable. After 35 years old, brain shrinks gradually. The changes of gray and white matters by aging show different features. N-acetylaspartate decreases or remains unchanged but choline, creatine and myo-inositol increase with aging. Apparent diffusion coefficient decreases till 20 years old and then becomes stable during adulthood and increase after 60 years old. Diffusion tensor properties in white matter tissue are variable during aging. Resting-state functional connectivity decreases after middle age. Structural and functional brain changes with normal aging are important for studying various psychiatric diseases such as dementia, schizophrenia and bipolar disorder. Our review may be helpful for studying longitudinal changes of these diseases and successful aging.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prótons
/
Esquizofrenia
/
Análise Espectral
/
Transtorno Bipolar
/
Encéfalo
/
Envelhecimento
/
Imageamento por Ressonância Magnética
/
Colina
/
Cognição
/
Creatina
Limite:
Adulto
/
Criança
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Biological Psychiatry
Ano de publicação:
2014
Tipo de documento:
Artigo
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