Vitamin K1 Dermatitis / 대한피부과학회지
Korean Journal of Dermatology
;
: 91-99, 1983.
Artigo
em Inglês
| WPRIM
| ID: wpr-72506
ABSTRACT
We observed allergic cutaneous reaction to vitsmin K, injection in 3 patients who developed pruritic erythematous indurated plaques at the sites of intramuscular injection and leakage sites of vitamin K1 preparation into dermis during IV injection 12 to 23 days after injection. Intradermal tests with vitamin K1,K3 and their placebos performed on 145 healthy medical students revealed positive skin reaction in 13 students 7 to 22 days after injection similar to the original 3 cases. Five students also showed the same reaction to vitarnin K1 placebo, however, a more severe reaction to vitamin K1 preparation than its placebo in 3 of them, indicating that the index of cutaneous sensitivity of vitamin K1 lies somewhere between 5. 5,% and 8. 9%. There was no cross sensitivity between vitamin K1 and K3 We consider these reactions to be of allergic nature.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vitamina K 1
/
Placebos
/
Pele
/
Estudantes de Medicina
/
Vitaminas
/
Testes Intradérmicos
/
Derme
/
Dermatite
/
Injeções Intramusculares
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Dermatology
Ano de publicação:
1983
Tipo de documento:
Artigo
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