P50 and Schizophrenia
Journal of the Korean Society of Biological Psychiatry
;
: 137-143, 2006.
Artigo
em Coreano
| WPRIM
| ID: wpr-725167
ABSTRACT
One of the most widely recognized neurophysiologic endophenotypes for schizophrenia is deficient gating or inhibition of the P50 component of the auditory event-related potential(ERP). A deficit in P50 sensory gating refers to a dysfunction in the mechanism responsible for modulating the brain's sensitivity of filtering out irrelevant or background stimuli, perhaps as a result of dysfunction in inhibitory neural circuits. In this paper, we review the neuronal and genetic aspects as well as medication effects on P50 in schizophrenia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esquizofrenia
/
Potenciais Evocados
/
Filtro Sensorial
/
Endofenótipos
/
Neurônios
Idioma:
Coreano
Revista:
Journal of the Korean Society of Biological Psychiatry
Ano de publicação:
2006
Tipo de documento:
Artigo
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