Current Understanding in Neurobiology of Depressive Disorders: Imaging Genetic Studies on Serotonin Transporter
Journal of the Korean Society of Biological Psychiatry
;
: 176-180, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-725331
ABSTRACT
Depressive disorders have strong genetic components. However, conventional linkage and association studies have not yielded definitive results. These might be due to the absence of objective diagnostic tests, the complex nature of human behavior or the incomplete penetrance of psychiatric traits. Imaging genetics explores the influences of genetic variation on the brain function or structure. This technique could provide a more sensitive assessment than traditional behavioral measures in psychiatric studies. Imaging genetics is a relatively new field of psychiatric researches, and may improve our understanding on neurobiology of psychiatric disorders. In this review, current understanding in neurobiology of depressive disorders, especially imaging genetic studies on serotonin transporter will be discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Variação Genética
/
Encéfalo
/
Neurobiologia
/
Serotonina
/
Penetrância
/
Transtorno Depressivo
/
Testes Diagnósticos de Rotina
/
Proteínas da Membrana Plasmática de Transporte de Serotonina
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Biological Psychiatry
Ano de publicação:
2011
Tipo de documento:
Artigo
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