Beta-Cell Function and Nutrient Intake / 임상당뇨병

ABSTRACT

Pancreatic beta-cells have an important role in maintaining blood glucose homeostasis through insulin secretion. Therefore, decreased insulin secretion function induced by impaired beta-cell is one of the leading causes of diabetes mellitus. Accumulating data suggested that multiple factors such as age, body weight, smoking and alcohol intake may decrease beta-cell function. In addition, previous studies have reported that nutrient intake, such as carbohydrate, fat, vitamin and mineral intake, is associated with beta-cell function. The purpose of this study is to review the results regarding the association between nutrient intake and beta-cell function. We propose herein that nutrient intake helps prevent decreases in beta-cell function and preserves the optimal insulin secretion function.