Ca2+-dependent exocytosis in endocine, exocrine, and nonsecretory cells
The Korean Journal of Physiology and Pharmacology
;
: 1-7, 1998.
Artigo
em Inglês
| WPRIM
| ID: wpr-728166
ABSTRACT
Exocytosis in various secretory cells is regulated by Ca2+ signaling. In this minireview, I will introduce our recent approach, which we have termed comparative biology of exocytosis, to the study of Ca2+-dependent secretion in such cells. In this approach, we quantify and compare the secretory process in different cell types (neurons, endocrine cells, and exocrine cells, with the same techniques. This approach benefits from the fact that the biochemistry and ultrastructure of these cells are relatively well characterized and it is expected to be particularly revealing because of the marked differences in the properties of exocytosis thought to exist among different secretory cells. The first part of this article deals with the mechanism by which Ca2+ signaling regulates exocytosis in exocrine cells, and the second part deals more generally with the diversity in the kinetics of the exocytotic machinery among different types of cells and secretory vesicles.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Bioquímica
/
Biologia
/
Cinética
/
Vesículas Secretórias
/
Exocitose
/
Células Endócrinas
/
Via Secretória
Idioma:
Inglês
Revista:
The Korean Journal of Physiology and Pharmacology
Ano de publicação:
1998
Tipo de documento:
Artigo
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