Nonanoic Acid, an Antifungal Compound from Hibiscus syriacus Ggoma
Mycobiology
;
: 145-146, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-729677
ABSTRACT
The root of Hibiscus syriacus (Malvaceae) has been used for treatment of fungal diseases such as tinea pedis (athlete's foot). In this study, we investigated the antifungal constituent of the root of Hibiscus syriacus Ggoma, which was produced by a mutation breeding using gamma ray irradiation, and compared the antifungal activity of H. syriacus Ggoma and its parent type. According to the results, the methanolic extract of H. syriacus Ggoma exhibited four times higher antifungal activity than its parent type against Trichophyton mentagrophytes. Following purification through various column chromatographies, the antifungal substance was identified as nonanoic acid on the basis of spectroscopic analysis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pais
/
Tinha dos Pés
/
Trichophyton
/
Cruzamento
/
Cromatografia
/
Hibiscus
/
Metanol
/
Ácidos Graxos
/
Raios gama
Limite:
Humanos
Idioma:
Inglês
Revista:
Mycobiology
Ano de publicação:
2012
Tipo de documento:
Artigo
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