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Chemical Constituents of the Culture Broth of Phellinus linteus and Their Antioxidant Activity
Mycobiology ; : 43-48, 2015.
Artigo em Inglês | WPRIM | ID: wpr-729862
ABSTRACT
The medicinal fungus Phellinus linteus, in the family Hymenochaetaceae, has been used as a traditional medicine for the treatment of various diseases. In this study, the chemical constituents of the culture broth of P. linteus were investigated. P. linteus was cultured in potato dextrose broth medium, and the culture broth was extracted with ethyl acetate. The ethyl acetate-soluble portion was concentrated and subjected to ODS column chromatography, followed by Sephadex LH-20 column chromatography. Six compounds (1~6) were purified by preparative reversed-phase high-performance liquid chromatography. Spectroscopic methods identified their structures as caffeic acid (1), inotilone (2), 4-(3,4-dihydroxyphenyl)-3-buten-2-one (3), phellilane H (4), (2E,4E)-(+)-4'-hydroxy-gamma-ionylideneacetic acid (5), and (2E,4E)-gamma-ionylideneacetic acid (6). Compounds 1, 2, and 3 exhibited potent dose-dependent antioxidant activity.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Solanum tuberosum / Cromatografia / Cromatografia Líquida / Fungos / Glucose / Medicina Tradicional Limite: Humanos Idioma: Inglês Revista: Mycobiology Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Solanum tuberosum / Cromatografia / Cromatografia Líquida / Fungos / Glucose / Medicina Tradicional Limite: Humanos Idioma: Inglês Revista: Mycobiology Ano de publicação: 2015 Tipo de documento: Artigo