Non-Syndromic Familial Supernumerary Teeth: Case Report And Review Of Their Phenotypic Characteristic

ABSTRACT

Supernumerary teeth have a genetic predispositionwith a predilection for males. This article reports anuncommon radiological finding in a non-syndromicsibling pair who presented with supernumerary teethof different morphologies on opposite and differentregions of the dental arches. A 14-year-old Chinesemale presented with a conical supernumerary palatallyplaced between the upper right central and lateralincisors. His older brother had unerupted bilateralsupplemental supernumerary teeth between the rootsof the lower second premolars and first permanentmolars. Trends of the phenotypic presentation offamilial non-syndromic supernumerary cases arediscussed. Familial supernumerary teeth have beensuggested to be due to autosomal dominance orrecessive traits. Variation in the numeral, spatial andmorphological phenotypic expressions suggests amultifactorial model of multiple genetic, epigeneticand environmental influences. Clinicians need to bemindful of the possible phenotypic variations that maypresent when treating cases with family history ofdental anomalies.