Inside-out vein graft vs autogenous nerve graft in promoting axonal regeneration: An experimental study in a rat model
Philippine Journal of Surgical Specialties
;
: 90-95, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-732574
ABSTRACT
BACKGROUND:
An experimental study was done to compare the efficacy of inside-out vein graft versus autogenous nerve graft as nerve conduit in promoting axonal regeneration in a rat model.METHODS:
The study used 16 Spraque-Dawley rats randomly divided into two groups the inside-out vein graft group and control group (autognous nerve graft). The outcomes measured were histomorphology (axon number and diameter), muscle twitch response (amplitude) and the walking track analysis at 2, 4 6 and 8 weeks.RESULTS:
The inverted vein graft and control groups showed similar axon diameter (P=0.76), and axon number (P=0.85), weeks and similar muscle twitch responses (P=0.87) after eight weeks. The walking track analysis showed no significant difference between the two groups at eight weeks.CONCLUSION:
The study showed that the inside-out vein graft group had similar motor recovery as compared to control group based on the muscle twitch analysis and walking track analysis in a rat model.In terms of histomorphometric analysis, the two groups were similar in terms of axon diameter and axon count.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Regeneração
/
Axônios
/
Veias
/
Caminhada
/
Fasciculação
/
Animais
Limite:
Animais
Idioma:
Inglês
Revista:
Philippine Journal of Surgical Specialties
Ano de publicação:
2013
Tipo de documento:
Artigo
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