Therapy strategy and prognosis in pediatric patients with severe Henoch-Sch(o)nlein purpura nephritis / 国际儿科学杂志

ABSTRACT

Henoch-Sch(o)nlein purpura nephritis (HSPN) is one of the most common types of secondary glomerulonephritis in children.Patients with severe HSPN are at distinctively higher risk of poor prognosis.Currently,no unified therapeutic method is adopted to treat severe HSPN,and disagreements exist in prognostic factors.This paper reviews the treatment measures including steroid,multiple immunosuppressive agents,rituximab and plasmapheresis for severe HSPN.Relevant factors for long-term prognosis of HSPN are discussed,which provide reference for clinical treatment and management.