Understanding and research progress of the correlation between long-chain non-coding RNA and tumor / 国际生物医学工程杂志

ABSTRACT

Long non-coding RNA (lncRNA) is a non-coding RNA with a length of more than 200 nucleotides that regulates gene expression.Studies have shown that lncRNA c is involved in a variety of cellular processes,including apoptosis regulation,tumor invasion and metastasis,which have certain carcinogenic or tumor suppressoreffects during tumorigenesis and development.lncRNA can also affect tumor cell growth through epigenetic regulation,and some lncRNAs are also associated with specific tumor types.At present,lncRNA is considered to be a potential,new tumor marker and a new target for future tumor treatment,and will have good clinical application value and prospect in tumor diagnosis and treatment.