A Case of Systemic Scleroderma Combined with Malignant Neoplasm / 대한피부과학회지

ABSTRACT

We report a 74-year-old female who showed systemic scleroderma and malignant neoplasm. She was diagnosed with cervical cancer and 6 months later, she developed dyspnea and sclerotic skin change. Anti Scl-70 antibody was positive. On radiologic study, both lungs showed pulmonary fibrosis and signs of metastatic lung cancer. The association of systemic scleroderma with malignant neoplasm is uncommon and has been considered to be coincidental. The reason for coincidence is unclear at present. But there is increasing evidence of an association between systemic scleroderma and maligant neoplasm.