Multivariate analysis of clinical characteristics and prognosis in pulmonary tuberculosis patients complicated with diabetes mellitus / 中国基层医药

ABSTRACT

Objective To study and analyze the clinical features of pulmonary tuberculosis complicated with diabetes,and the risk factors affecting the prognosis of pulmonary tuberculosis patients complicated with diabetes by multivariate analysis.Methods From January 2012 to January 2015,200 tuberculosis patients complicated with diabetes in the Second Hospital of Yuncheng were selected in the research.The clinical data of 200 patients were retrospectively analyzed,the clinical characteristics of pulmonary tuberculosis with diabetes (age,gender,lung cavity etc) were summarized,the 2-year follow-up data were analyzed to analyze the recurrence.The patients were divid-ed into good prognosis group and poor prognosis group.The clinical data were compared between the two groups,multi-variate analysis and logistics regression analysis were used to analyze the risk factors affecting prognosis of pulmonary tuberculosis patients with diabetes.Results The distribution of pulmonary tuberculosis patients with diabetes in males was higher than females (P＜0.05),the age distribution was mainly over 60 years old,the incidence rate of lung cavity was 67.50%,the positive rate of sputum was 64.00%.After 2 years of follow-up,there were 42 cases of recurrence.Univariate analysis results showed that there were statistically significant differences in age,blood glucose control effect,drug resistance,drug compliance and other aspects between the poor prognosis group and the good prog -nosis group (all P＜0.05),and there were no statistically significant differences in gender,lung cavities,sputum posi-tive aspects between the two groups (all P＞0.05).The logistics linear regression analysis showed that the effect of blood glucose control,drug resistance and compliance were the risk factors affecting prognosis of pulmonary tuberculosis patients with diabetes.Conclusion Pulmonary tuberculosis complicated with diabetes occurred in elderly male popu-lation,the prognosis is often affected by effect of blood glucose control,drug resistance,medication compliance and other factors,clinical intervention should be carried out according to the prognostic risk factors.